tobiasgf/lulu: Post Clustering Curation of Amplicon Data for Reliable Biodiversity Metrics

The LULU algorithm excludes artefactual OTUs without discarding rare, but real OTUs. The core mechanism is the identification and merging of ‘daughter’ OTUs with consistently co-occurring, sequence-similar, but more abundant ‘parent’ OTUs across a multi-sample dataset, under the assumption that the ‘daughter’ OTUs are artefacts. The algorithm is independent of a reference database, and can thus be applied to any OTU table produced for any set of samples with any initial OTU definition algorithm.

Getting started

Package details

MaintainerThe package maintainer <>
LicenseGNU General Public License v3 (GPL-3)
Package repositoryView on GitHub
Installation Install the latest version of this package by entering the following in R:
tobiasgf/lulu documentation built on May 24, 2019, 7:31 a.m.