The LULU algorithm excludes artefactual OTUs without discarding rare, but real OTUs. The core mechanism is the identification and merging of ‘daughter’ OTUs with consistently co-occurring, sequence-similar, but more abundant ‘parent’ OTUs across a multi-sample dataset, under the assumption that the ‘daughter’ OTUs are artefacts. The algorithm is independent of a reference database, and can thus be applied to any OTU table produced for any set of samples with any initial OTU definition algorithm.
|Maintainer||The package maintainer <[email protected]>|
|License||GNU General Public License v3 (GPL-3)|
|Package repository||View on GitHub|
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