get_recruittimes: get_recruittimes

In tobiasmuetze/gscounts: Group Sequential Designs with Negative Binomial Outcomes

get_recruittimes

Description

Calculate the times subjects enter the study

Usage

get_recruittimes(accrual_period, n, accrual_exponent)

Arguments

accrual_period	numeric; duration of accrual period. Must be positive.
n	numeric; number of subjects recruited at end of accrual period.
accrual_exponent	numeric; exponent in sample size function f(t).

Details

Number of subjects in the study at study time t is given by f(t)=a * t^b with a = n / accrual_period. For linear recruitment, b=1. b > 1 results is slower than linear recruitment for t < accrual_period and faster than linear recruitment for t > accrual_period. b < 1 vice versa.

tobiasmuetze/gscounts documentation built on Sept. 10, 2023, 7:30 a.m.