HIV_data: HIV Drug Resistance Database

In ubclxing/MTPS: Multi-Task Prediction using Stacking Algorithms

Description

The data from HIV Drug Resistance Database used for demonstration. After processing, YY contains 5 response variables variable for 1246 observations and XX are 228 predictors of those 1246 obsevations.

Format

Data objects used for demonstration

Details

In the HIV database, the resistance of five Nucleoside RT Inhibitor (NRTI) drugs were used as multivariate outcomes, including Lamivudine (3TC), Abacavir(ABC), Zidovudine (AZT), Stavudine (D4T), Didanosine (DDI). The mutation variables are used as the predictors. Some mutation variables were removed as they do not contain enough variation. The final outcome data is a matrix of size 1246 × 5, and the predictor data is a matrix of 1246 × 228 values, which is provided in the package called "HIV". In the example data in the package, "YY" refers the outcome data and "XX" refers the predictor data.

References

S Y Rhee, J Taylor, G Wadhera, A Ben-Hur, D L Brutlag, and R W Shafer. Genotypic predictors of human immunodeficiency virus type 1 drug resistance. Proceedings of the National Academy of Sciences of the United States of America, 103(46):17355–17360, November 2006

Examples

data(HIV)

ubclxing/MTPS documentation built on Sept. 26, 2019, 5:31 p.m.