call LiMACC algorithm
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index_file |
the name of restriction enzyme file for CHiC or index_file for HiChIP |
count_file |
contact map file(s) |
out_filename |
output file name |
comb_rep |
if length(count_file)>1, merge or pool replicates (default merge for CHiC; pool for HiChIP) |
dtype |
data type, CHiC/CC/HiChIP |
peakFile4HiChIP |
file of coordinate of 1D peak (bed file or similar format) for HiChIP, NULL for other type of data |
numG |
number of groups for limacc (default 100) |
hcrc_pr |
initial guess of backgound (default 0.9) |
fdr |
fdr cutoff used for the final output (default 0.05) |
nIter |
maxmimum number of iterations (default 20) |
maxN |
filter contacts that wiht more than maxN counts (default 100) |
minLen |
filter otherEnd fragments with length smaller than minLen |
maxLen |
filter otherEnd fragments with length greater than maxLen |
adj.method |
method for adjusting p-value (default 'IHW') |
updateMethod |
smooth or noupdate (default 'smooth') |
sdepth |
the number (in million) to which the sequence depth should be normalized, default NULL means do not adjust the total sequence depth |
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