Description Usage Arguments Value
generate simulated hic_mat and true tads
1 2 | data_simu(stype = "poisson-dist", nratio = 2.5, mu0 = 200,
resl = 1)
|
stype |
One of four types of simulated data in the manuscript: poission-dist, poission-dist-hier, nb-dist, nb-dist-hier; poission- or nb- indicates poission distribution or negative bionomial distribution -hier indicated subtads are generated nestly |
nratio |
The effect size between intra- and inter domain, larger means higher intra-tad contacts |
mu0 |
The mean parameter, default 200 |
resl |
Resolution, default set to 1 |
A list includes following elements:
hic_mat |
n by n contact matrix |
hierTads |
True heirarchical domains |
tads_true |
True TADs |
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