R/amd.R

##
## clusrank: Wilcoxon Rank Tests for Clustered Data
##
## Copyright (C) 2015-2024 Yujing Jiang, Mei-Ling Ting Lee, and Jun Yan
## Copyright (C) 2022-2024 Wenjie Wang
##
## This file is part of the R package clusrank.
##
## The R package clusrank is free software: You can redistribute it and/or
## modify it under the terms of the GNU General Public License as published by
## the Free Software Foundation, either version 3 of the License, or any later
## version (at your option). See the GNU General Public License at
## <https://www.gnu.org/licenses/> for details.
##
## The R package clusrank is distributed in the hope that it will be useful,
## but WITHOUT ANY WARRANTY without even the implied warranty of
## MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.
##


##' CARMS scores
##'
##' A data set from a research on complement factor H R1210C rare variant and
##' its associated phenotype.  This data set contains Clinical Age-Related
##' Maculopathy Staging (CARMS) scores from a total of 143 patients (283 eyes)
##' including 62 patients with the rare variant. The data is from the lab of
##' Dr. Johanna M. Seddon,
##'
##' @format A data frame with 283 rows and 7 variables.
##'
##' \itemize{
##'   \item  ID patient identifier
##' \item  Eye OD (right eye), OS(left eye)
##' \item  Variant 1: No R1210C Variant; 2: R1210C Variant
##' \item CARMS Patient's last CARMS grade, related to age-related
##'     macular degeneration (AMD). 1: no AMD; 2: early AMD; 3:
##'     intermediate AMD;  4: geographic atroph(advanced dry); 5:
##'     neovascular disease (advanced wet)
##' \item Age_group 1: < 70 years;  2: 70 to 79.9 years; 3: >= 80 years
##' \item Sex 1: male; 2: female
##' \item AgeSex 1: agegroup = 1, sex = 1;  2: agegroup = 2, sex = 1;
##'     3: agegroup = 3, sex = 1; 4: agegroup = 1, sex = 2; 5: agegroup
##'     = 2, sex = 2; 6: agegroup = 3, sex = 2;
##' }
##'
##' @name amd
##' @docType data
##' @note CARMS grades were assessed separately for
##' the two advanced stages (4 and 5):
##' 1. CARMS 1,2,3, and 4 was assessed;
##' 2. CARMS 1,2,3, and 5 was assessed
##' @source The data came from Seddon's lab.
##' @references  Seddon JM, Sharma S, Adelman RA (2006)
##' \emph{Evaluation of the Clinical Age-related
##'  Maculopathy Staging System.}
##' Ophthalmology, \bold{113}, 260-266.
##' @references Ferrara D, Seddon JM (2015)
##' \emph{ Phenotypic characterization of complement
##' factor H R1210C rare genetic variant in
##' age-related macular degeneration}
##' JAMA Ophthalmol, 2015 Apr 16.
##' doi:10.1001/jamaophthalmol.2015.0814.
##' @examples
##' data(amd)
##' clusWilcox.test(CARMS ~ Variant + cluster(ID), data = amd,
##'                subset = CARMS %in% c(1, 2, 3, 4), method = "rgl", alternative = "two")
##' clusWilcox.test(CARMS ~ Variant + cluster(ID), data = amd,
##'                subset = CARMS %in% c(1, 2, 3, 4), method = "ds", alternative = "two")
##' clusWilcox.test(CARMS ~ Variant + cluster(ID) + stratum(AgeSex), data = amd,
##'                subset = CARMS %in% c(1, 2, 3, 4), alternative = "two")
##' @keywords datasets
NULL
wenjie2wang/clusrank documentation built on Feb. 22, 2024, 4:34 a.m.