IdentifyVariableEvents: Identify highly variable splicing events

In wenweixiong/MARVEL: Revealing Splicing Dynamics at Single-Cell Resolution

Identify highly variable splicing events

Description

Identify highly variable splicing events by fitting spline model. The vector splicing events returned may be used for downstream dimension reduction analysis with the RunPCA function.

Usage

IdentifyVariableEvents(
  MarvelObject,
  sample.ids = NULL,
  cell.group.column,
  cell.group.order,
  min.cells = 25
)

Arguments

MarvelObject	Marvel object. S3 object generated from ComputePSI function.
sample.ids	Character strings. Specific cells to plot.
cell.group.column	Character string. The name of the sample metadata column in which the variables will be used included for analysis
cell.group.order	Character string. The the variables under the sample metadata column specified in cell.group.column to be included for analysis
min.cells	Numeric value. The minimum no. of cells expressing the splicing event, above which, the splicing event will be retained for analysis.

Value

An object of class S3 containing with new slots MarvelObject$VariableSplicing$tran_ids and MarvelObject$VariableSplicing$plot

wenweixiong/MARVEL documentation built on Aug. 5, 2024, 2:54 p.m.