Perform_HTMMIOW: Perform HT-MMIOW

In yukamoro/HTMMIOW: Hypothesis Test for Microbiome Mediation using Inverse Odds Weighting

Perform HT-MMIOW

Description

This function performs HT-MMIOW on user-provided exposure, outcome, confounder, and mediator data.

Usage

Perform_HTMMIOW(
  exposure,
  outcome,
  confounder = NULL,
  mediator,
  umapcomponents = 2,
  B = 2000
)

Arguments

exposure	vector of exposure variable
outcome	vector of outcome variable
confounder	matrix of relavant covariates
mediator	matrix of integers that represent abundance
umapcomponents	number of components for UMAP to reduce to
B	number of replicates for hypothesis test

Value

A list of observed test statistic, p-value, and test statistics under the null hypothesis

Examples

Perform_HTMMIOW(exposure = sim_data$sim_exposure,
outcome = sim_data$sim_outcome,
mediator = sim_data$sim_microbiome,
umapcomponents = 2)

yukamoro/HTMMIOW documentation built on May 5, 2022, 6:47 a.m.