sim_cont: Data simulation

In yuliasidi/nibinom:

Description

Simulates data for noninferiority trials with binomal proportions.

Usage

sim_cont(p_C, p_T, n_arm, mu1, mu2, sigma1, sigma2, r12, b1, b2)

Arguments

p_C	numeric, Probsability of events in control arm
p_T	numeric, Probsability of events in treatment arm
n_arm	numeric, number of observations per arm (balanced)
mu1	numeric, mean of continuous covariate 1 at baseline
mu2	numeric, mean of continuous covariate 2 at baseline
sigma1	numeric, standard deviation of continuous covariate 1 at baseline
sigma2	numeric, standard deviation of continuous covariate 2 at baseline
r12	numeric, correlation between covariate 1 and 2
b1	numeric, effect of covariate 1 on the outcome
b2	numeric, effect of covariate 2 on the outcome

Details

The output contains a tibble with 6 columns: pat_id, trt, trtn, y, x1, x2.

Value

tibble

See Also

mvrnorm tibble Uniform

Examples

 sim_cont(
 p_C = 0.6, p_T = 0.5, n_arm = 200,
 mu1 = 4, mu2 = 100, sigma1 = 1,
 sigma2 = 20, r12 = -0.3,
 b1 = 0.1, b2 = -0.01)

yuliasidi/nibinom documentation built on Dec. 14, 2021, 11:43 p.m.