README.md

In yuy113/wActNet: Detection of active subnetwork in metabolic weighted network

wActNet

An R package to detect (possible multiple) active subnetwork(s)-potential functional module based on node scores and edge scores in metabolic weighted network. Detect optimized subnetworks-potential function modules based on weighted sum of node scores and edge scores where node scores are derived from P values of multiple testing on individual nodes (metabolites) with some outcome; and edge scores are derived from P values of permutation tests on pairwise correlations among all possible connecting edges in the whole metabolic network.Also we can detect multiple optimized subnetworks with either node scores only or combining node scores with edge scores with prespecified number of optimized neworks-signaling clusters in the whole network.

A quick user guidance of R package wActNet is below:

https://yuy113.github.io/Web/wActNetQuickGuidance.html

yuy113/wActNet documentation built on Sept. 30, 2024, 5:50 a.m.