CoxFlex: Estimate the TD and/or NL effect(s) of continuous...

CoxFlexR Documentation

Estimate the TD and/or NL effect(s) of continuous covariate(s) in time-to-event analysis

Description

Estimate the TD and/or NL effect(s) of continuous covariate(s) in time-to-event analysis

Usage

CoxFlex(data, Type, variables, TD, NL, m, p, knots)

Arguments

data

A data frame in the long (interval) format with one line per unit of time.

Type

A vector consisting the name of variables representing the start and stop of each time interval and event indicator. e.g. c("start","stop","event").

variables

A vector consisting the name of varialbes that will be adjusted in the model.

TD

A vector of binary indicators representing whether the corresponding variable has a time-dependent effect or not (1=Yes, 0=No)

NL

A vector of binary indicators representing whether the corresponding variable has a non-linear effect or not (1=Yes, 0=No)

m

The number of interior knots used in the regression B-spline

p

The degree of the regression B-spline

knots

Default value is -999

Value

Returns a list of the following items:

PLL

partial loglikelihood of the final model

NP

number of parameters estimated in the model

NE

number of events in the dataset

knots_covariates

knots for splines of NL effects for corresponding covariates

knots_time

knots for splines of the TD effect

coefficients_splines_NL

estimated splines coefficients for NL effects

coefficients_splines_TD

estimated splines coefficients for TD effects

variables

name of the covariates in the order they are adjusted in the model

coef

estimated coefficients for covariates not having TD and NL effects

sd

standard errors of the corresponding estimated coefficients

pval

p-values for corresponding estimated effects

Note

Note that the TD and NL arguments have different meanings than that in the BackSelection()


ywang297/CoxFlex documentation built on March 18, 2024, 3:26 a.m.