MAPS-package: A multi-locus genetic association test for a dichotomous...
In zhangh12/MAPS: Multi-locus Association test for a Primary trait and its Secondary phenotype
Description
Details
Author(s)
References
Description
The dichotomous trait could be the disease status from a prospective cohort study or from a retrospective case-control study. The quantitative secondary phenotype is assumed to be only collected on the subjects with disease condition. This test is only allow one secondary phenotype.
Details
Package: MAPS
Type: Package
Version: 0.1.10
Date: 2015-01-22
License: GPL-3
The proposed test can be performed through the function maps. A multi-locus score test generalized from Wu's single-marker test is implemented in function wu. Notice that when there is only one SNP, wu is actually the test in Wu et al. (2013). The function gforest can generate the forest plot for each SNP specified in the formula
Author(s)
Han Zhang and Yifan Yang
Maintainer: Han Zhang <han.zhang2@nih.gov>
References
Zhang, H., Wu, C.O., Yang, Y., Berndt, S., and Yu K. (2015) A multi-locus genetic association test for a dichotomous trait and its secondary phenotype. Submitted.
Wu, C.O., Zheng, G., and Kwak, M. (2013) A joint regression analysis for genetic association studies with outcome stratified samples. Biometrics 69, 417–426.
zhangh12/MAPS documentation built on May 4, 2019, 10:16 p.m.
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Description Details Author(s) References
Description
The dichotomous trait could be the disease status from a prospective cohort study or from a retrospective case-control study. The quantitative secondary phenotype is assumed to be only collected on the subjects with disease condition. This test is only allow one secondary phenotype.
Details
| Package: | MAPS |
| Type: | Package |
| Version: | 0.1.10 |
| Date: | 2015-01-22 |
| License: | GPL-3 |
The proposed test can be performed through the function maps. A multi-locus score test generalized from Wu's single-marker test is implemented in function wu. Notice that when there is only one SNP, wu is actually the test in Wu et al. (2013). The function gforest can generate the forest plot for each SNP specified in the formula
Author(s)
Han Zhang and Yifan Yang
Maintainer: Han Zhang <han.zhang2@nih.gov>
References
Zhang, H., Wu, C.O., Yang, Y., Berndt, S., and Yu K. (2015) A multi-locus genetic association test for a dichotomous trait and its secondary phenotype. Submitted.
Wu, C.O., Zheng, G., and Kwak, M. (2013) A joint regression analysis for genetic association studies with outcome stratified samples. Biometrics 69, 417–426.
R Package Documentation
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