zhouhj1994/LinDA: Linear model for differential abundance analysis

The package implements a simple, robust and highly scalable approach to tackle the compositional effects in differential abundance analysis. It fits linear regression models on the centered log2-ratio transformed data, identifies a bias term due to the transformation and compositional effect, and corrects the bias using the mode of the regression coefficients. It could fit mixed-effect models.

install.packages("remotes")
remotes::install_github("zhouhj1994/LinDA")