PwrGSD: Power in a Group Sequential Design

Tools the evaluation of interim analysis plans for sequentially monitored trials on a survival endpoint; tools to construct efficacy and futility boundaries, for deriving power of a sequential design at a specified alternative, template for evaluating the performance of candidate plans at a set of time varying alternatives.

AuthorGrant Izmirlian
Date of publicationNone
MaintainerGrant Izmirlian <izmirlig@mail.nih.gov>
LicenseGPL (>= 2)
Version1.16

View on R-Forge

Man pages

Ch1-PwrGSD: Calculate Power in a Group Sequential Design

Ch2-LanDemets: The Lan-Demets method of Boundary Construction

Ch3-ObrienFleming: The O'Brien-Fleming Alpha Spending Function

Ch4-Pow: The Wang-Tsiatis Power Alpha Spending Function

Ch5-Pocock: The Pocock Alpha Spending Function

Ch6-SC: The Stochastic Curtailment method of Boundary Construction

Ch7-Haybittle: The Haybittle method of Boundary Construction

Ch8-cpd.PwrGSD: Create a skeleton compound PwrGSD object

Ch9-Power: Extract the Power results

ChA1-as.boundaries: Convert a "PwrGSD" object to a "boundaries" object

ChA2-Elements: Create a subset of a "cpd.PwrGSD" object

ChA3-plot.cpd.PwrGSD: Plot Method for cpd.PwrGSD objects

ChA4-GrpSeqBnds: Computes efficacy and futility boundaries

ChA5-CondPower: Conditional type I and type II error probabilities given...

ChA6-SimGSB: Verifies the results of "GrpSeqBnds" via simulation

ChA7-wtdlogrank: Weighted log-rank test

ChA8-IntSurvDiff: Weighted Integrated Survival function test

ChA9-agghaz: Aggregated Hazard

ChB1-mysurvfit: My Survfit

ChB2-mystack: Stack a dataset

ChB3-CDFOR2LRR: Convert CDF Odds Ratio to Logged Relative Risks

ChB4-CY2TOShaz: Calender year rates to Study Year Rates

ChB5-CRRtoRR: Cumulative-risk ratios to risk ratios

ChB6-RCM2RR: Relative cumulative mortality to Relative Risk

ChB7-RR2RCM: Relative risk to Relative Cumulative Mortality

ChB8-lookup: Lookup values for a piecewise constant function

ChB9-lung: Mayo Clinic Lung Cancer Data

ChC1-DX: A utility function for forming differences

ChC2-pste: The paste operator

Files in this package

PwrGSD
PwrGSD/INDEX
PwrGSD/data
PwrGSD/data/lung.rda
PwrGSD/R
PwrGSD/R/PwrGSD.R
PwrGSD/NAMESPACE
PwrGSD/inst
PwrGSD/inst/doc
PwrGSD/inst/doc/PwrGSD-vignette-1.pdf
PwrGSD/inst/doc/GrpSeqBnds-vignette-1.Rnw
PwrGSD/inst/doc/PwrGSD-vignette-1.Rnw
PwrGSD/inst/doc/GrpSeqBnds-vignette-1-incl-ex1-plot.eps
PwrGSD/inst/doc/GrpSeqBnds-vignette-1.pdf
PwrGSD/inst/doc/PwrGSD-manual.pdf
PwrGSD/inst/doc/cpd-PwrGSD-vignette-1.pdf
PwrGSD/inst/doc/cpd-PwrGSD-vignette-1.Rnw
PwrGSD/inst/doc/stats.txt
PwrGSD/DESCRIPTION
PwrGSD/man
PwrGSD/man/ChA6-SimGSB.Rd PwrGSD/man/ChB8-lookup.Rd PwrGSD/man/Ch1-PwrGSD.Rd PwrGSD/man/ChB2-mystack.Rd PwrGSD/man/ChA2-Elements.Rd PwrGSD/man/ChB3-CDFOR2LRR.Rd PwrGSD/man/Ch6-SC.Rd PwrGSD/man/ChA7-wtdlogrank.Rd PwrGSD/man/Ch8-cpd.PwrGSD.Rd PwrGSD/man/ChB5-CRRtoRR.Rd PwrGSD/man/ChB7-RR2RCM.Rd PwrGSD/man/Ch9-Power.Rd PwrGSD/man/Ch4-Pow.Rd PwrGSD/man/ChB1-mysurvfit.Rd PwrGSD/man/ChB4-CY2TOShaz.Rd PwrGSD/man/ChA3-plot.cpd.PwrGSD.Rd PwrGSD/man/ChA9-agghaz.Rd PwrGSD/man/ChB9-lung.Rd PwrGSD/man/ChA8-IntSurvDiff.Rd PwrGSD/man/Ch5-Pocock.Rd PwrGSD/man/ChC1-DX.Rd PwrGSD/man/ChC2-pste.Rd PwrGSD/man/Ch7-Haybittle.Rd PwrGSD/man/ChA5-CondPower.Rd PwrGSD/man/Ch2-LanDemets.Rd PwrGSD/man/ChB6-RCM2RR.Rd PwrGSD/man/Ch3-ObrienFleming.Rd PwrGSD/man/ChA4-GrpSeqBnds.Rd PwrGSD/man/ChA1-as.boundaries.Rd
PwrGSD/src
PwrGSD/src/lookup.c
PwrGSD/src/cpblocked.c
PwrGSD/src/WtdLogRank.c
PwrGSD/src/StCu2Bnds.c
PwrGSD/src/mystack.c
PwrGSD/src/AsyPwrGSD.c
PwrGSD/src/drift.c
PwrGSD/src/cmptdnsty.c
PwrGSD/src/MySurvFit.c
PwrGSD/src/SimPwrGSD.c
PwrGSD/src/trand.c
PwrGSD/src/driftfu.c
PwrGSD/src/cmptpwrgsd.c
PwrGSD/src/grpseqbnds.c
PwrGSD/src/htilde.c
PwrGSD/src/intsurvdiff.c
PwrGSD/src/Finv.c
PwrGSD/src/Dnsties.c
PwrGSD/src/agghaz.c

Questions? Problems? Suggestions? or email at ian@mutexlabs.com.

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