PwrGSD: Power in a Group Sequential Design

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Tools the evaluation of interim analysis plans for sequentially monitored trials on a survival endpoint; tools to construct efficacy and futility boundaries, for deriving power of a sequential design at a specified alternative, template for evaluating the performance of candidate plans at a set of time varying alternatives.

Author
Grant Izmirlian
Date of publication
None
Maintainer
Grant Izmirlian <izmirlig@mail.nih.gov>
License
GPL (>= 2)
Version
1.16

View on R-Forge

Man pages

Ch1-PwrGSD
Calculate Power in a Group Sequential Design
Ch2-LanDemets
The Lan-Demets method of Boundary Construction
Ch3-ObrienFleming
The O'Brien-Fleming Alpha Spending Function
Ch4-Pow
The Wang-Tsiatis Power Alpha Spending Function
Ch5-Pocock
The Pocock Alpha Spending Function
Ch6-SC
The Stochastic Curtailment method of Boundary Construction
Ch7-Haybittle
The Haybittle method of Boundary Construction
Ch8-cpd.PwrGSD
Create a skeleton compound PwrGSD object
Ch9-Power
Extract the Power results
ChA1-as.boundaries
Convert a "PwrGSD" object to a "boundaries" object
ChA2-Elements
Create a subset of a "cpd.PwrGSD" object
ChA3-plot.cpd.PwrGSD
Plot Method for cpd.PwrGSD objects
ChA4-GrpSeqBnds
Computes efficacy and futility boundaries
ChA5-CondPower
Conditional type I and type II error probabilities given...
ChA6-SimGSB
Verifies the results of "GrpSeqBnds" via simulation
ChA7-wtdlogrank
Weighted log-rank test
ChA8-IntSurvDiff
Weighted Integrated Survival function test
ChA9-agghaz
Aggregated Hazard
ChB1-mysurvfit
My Survfit
ChB2-mystack
Stack a dataset
ChB3-CDFOR2LRR
Convert CDF Odds Ratio to Logged Relative Risks
ChB4-CY2TOShaz
Calender year rates to Study Year Rates
ChB5-CRRtoRR
Cumulative-risk ratios to risk ratios
ChB6-RCM2RR
Relative cumulative mortality to Relative Risk
ChB7-RR2RCM
Relative risk to Relative Cumulative Mortality
ChB8-lookup
Lookup values for a piecewise constant function
ChB9-lung
Mayo Clinic Lung Cancer Data
ChC1-DX
A utility function for forming differences
ChC2-pste
The paste operator

Files in this package

PwrGSD
PwrGSD/INDEX
PwrGSD/data
PwrGSD/data/lung.rda
PwrGSD/R
PwrGSD/R/PwrGSD.R
PwrGSD/NAMESPACE
PwrGSD/inst
PwrGSD/inst/doc
PwrGSD/inst/doc/PwrGSD-vignette-1.pdf
PwrGSD/inst/doc/GrpSeqBnds-vignette-1.Rnw
PwrGSD/inst/doc/PwrGSD-vignette-1.Rnw
PwrGSD/inst/doc/GrpSeqBnds-vignette-1-incl-ex1-plot.eps
PwrGSD/inst/doc/GrpSeqBnds-vignette-1.pdf
PwrGSD/inst/doc/PwrGSD-manual.pdf
PwrGSD/inst/doc/cpd-PwrGSD-vignette-1.pdf
PwrGSD/inst/doc/cpd-PwrGSD-vignette-1.Rnw
PwrGSD/inst/doc/stats.txt
PwrGSD/DESCRIPTION
PwrGSD/man
PwrGSD/man/ChA6-SimGSB.Rd
PwrGSD/man/ChB8-lookup.Rd
PwrGSD/man/Ch1-PwrGSD.Rd
PwrGSD/man/ChB2-mystack.Rd
PwrGSD/man/ChA2-Elements.Rd
PwrGSD/man/ChB3-CDFOR2LRR.Rd
PwrGSD/man/Ch6-SC.Rd
PwrGSD/man/ChA7-wtdlogrank.Rd
PwrGSD/man/Ch8-cpd.PwrGSD.Rd
PwrGSD/man/ChB5-CRRtoRR.Rd
PwrGSD/man/ChB7-RR2RCM.Rd
PwrGSD/man/Ch9-Power.Rd
PwrGSD/man/Ch4-Pow.Rd
PwrGSD/man/ChB1-mysurvfit.Rd
PwrGSD/man/ChB4-CY2TOShaz.Rd
PwrGSD/man/ChA3-plot.cpd.PwrGSD.Rd
PwrGSD/man/ChA9-agghaz.Rd
PwrGSD/man/ChB9-lung.Rd
PwrGSD/man/ChA8-IntSurvDiff.Rd
PwrGSD/man/Ch5-Pocock.Rd
PwrGSD/man/ChC1-DX.Rd
PwrGSD/man/ChC2-pste.Rd
PwrGSD/man/Ch7-Haybittle.Rd
PwrGSD/man/ChA5-CondPower.Rd
PwrGSD/man/Ch2-LanDemets.Rd
PwrGSD/man/ChB6-RCM2RR.Rd
PwrGSD/man/Ch3-ObrienFleming.Rd
PwrGSD/man/ChA4-GrpSeqBnds.Rd
PwrGSD/man/ChA1-as.boundaries.Rd
PwrGSD/src
PwrGSD/src/lookup.c
PwrGSD/src/cpblocked.c
PwrGSD/src/WtdLogRank.c
PwrGSD/src/StCu2Bnds.c
PwrGSD/src/mystack.c
PwrGSD/src/AsyPwrGSD.c
PwrGSD/src/drift.c
PwrGSD/src/cmptdnsty.c
PwrGSD/src/MySurvFit.c
PwrGSD/src/SimPwrGSD.c
PwrGSD/src/trand.c
PwrGSD/src/driftfu.c
PwrGSD/src/cmptpwrgsd.c
PwrGSD/src/grpseqbnds.c
PwrGSD/src/htilde.c
PwrGSD/src/intsurvdiff.c
PwrGSD/src/Finv.c
PwrGSD/src/Dnsties.c
PwrGSD/src/agghaz.c