PwrGSD: Power in a Group Sequential Design

Tools the evaluation of interim analysis plans for sequentially monitored trials on a survival endpoint; tools to construct efficacy and futility boundaries, for deriving power of a sequential design at a specified alternative, template for evaluating the performance of candidate plans at a set of time varying alternatives.

AuthorGrant Izmirlian
Date of publicationNone
MaintainerGrant Izmirlian <izmirlig@mail.nih.gov>
LicenseGPL (>= 2)
Version1.16

View on R-Forge

Man pages

Ch1-PwrGSD: Calculate Power in a Group Sequential Design

Ch2-LanDemets: The Lan-Demets method of Boundary Construction

Ch3-ObrienFleming: The O'Brien-Fleming Alpha Spending Function

Ch4-Pow: The Wang-Tsiatis Power Alpha Spending Function

Ch5-Pocock: The Pocock Alpha Spending Function

Ch6-SC: The Stochastic Curtailment method of Boundary Construction

Ch7-Haybittle: The Haybittle method of Boundary Construction

Ch8-cpd.PwrGSD: Create a skeleton compound PwrGSD object

Ch9-Power: Extract the Power results

ChA1-as.boundaries: Convert a "PwrGSD" object to a "boundaries" object

ChA2-Elements: Create a subset of a "cpd.PwrGSD" object

ChA3-plot.cpd.PwrGSD: Plot Method for cpd.PwrGSD objects

ChA4-GrpSeqBnds: Computes efficacy and futility boundaries

ChA5-CondPower: Conditional type I and type II error probabilities given...

ChA6-SimGSB: Verifies the results of "GrpSeqBnds" via simulation

ChA7-wtdlogrank: Weighted log-rank test

ChA8-IntSurvDiff: Weighted Integrated Survival function test

ChA9-agghaz: Aggregated Hazard

ChB1-mysurvfit: My Survfit

ChB2-mystack: Stack a dataset

ChB3-CDFOR2LRR: Convert CDF Odds Ratio to Logged Relative Risks

ChB4-CY2TOShaz: Calender year rates to Study Year Rates

ChB5-CRRtoRR: Cumulative-risk ratios to risk ratios

ChB6-RCM2RR: Relative cumulative mortality to Relative Risk

ChB7-RR2RCM: Relative risk to Relative Cumulative Mortality

ChB8-lookup: Lookup values for a piecewise constant function

ChB9-lung: Mayo Clinic Lung Cancer Data

ChC1-DX: A utility function for forming differences

ChC2-pste: The paste operator

Functions

\%,\% Man page
agghaz Man page
as.boundaries Man page
CDFOR2LRR Man page
CondPower Man page
cpd.PwrGSD Man page
CRRtoRR Man page
CY2TOShaz Man page
DX Man page
Elements Man page
GrpSeqBnds Man page
Haybittle Man page
IntSurvDiff Man page
LanDemets Man page
lookup Man page
lung Man page
mystack Man page
mysurvfit Man page
ObrienFleming Man page
paste Man page
plot.cpd.PwrGSD Man page
Pocock Man page
Pow Man page
Power Man page
PwrGSD Man page
RCM2RR Man page
RR2RCM Man page
SC Man page
SimGSB Man page
wtdlogrank Man page

Files

INDEX
data
data/lung.rda
R
R/PwrGSD.R
NAMESPACE
inst
inst/doc
inst/doc/PwrGSD-vignette-1.pdf
inst/doc/GrpSeqBnds-vignette-1.Rnw
inst/doc/PwrGSD-vignette-1.Rnw
inst/doc/GrpSeqBnds-vignette-1-incl-ex1-plot.eps
inst/doc/GrpSeqBnds-vignette-1.pdf
inst/doc/PwrGSD-manual.pdf
inst/doc/cpd-PwrGSD-vignette-1.pdf
inst/doc/cpd-PwrGSD-vignette-1.Rnw
inst/doc/stats.txt
DESCRIPTION
man
man/ChA6-SimGSB.Rd man/ChB8-lookup.Rd man/Ch1-PwrGSD.Rd man/ChB2-mystack.Rd man/ChA2-Elements.Rd man/ChB3-CDFOR2LRR.Rd man/Ch6-SC.Rd man/ChA7-wtdlogrank.Rd man/Ch8-cpd.PwrGSD.Rd man/ChB5-CRRtoRR.Rd man/ChB7-RR2RCM.Rd man/Ch9-Power.Rd man/Ch4-Pow.Rd man/ChB1-mysurvfit.Rd man/ChB4-CY2TOShaz.Rd man/ChA3-plot.cpd.PwrGSD.Rd man/ChA9-agghaz.Rd man/ChB9-lung.Rd man/ChA8-IntSurvDiff.Rd man/Ch5-Pocock.Rd man/ChC1-DX.Rd man/ChC2-pste.Rd man/Ch7-Haybittle.Rd man/ChA5-CondPower.Rd man/Ch2-LanDemets.Rd man/ChB6-RCM2RR.Rd man/Ch3-ObrienFleming.Rd man/ChA4-GrpSeqBnds.Rd man/ChA1-as.boundaries.Rd
src
src/lookup.c
src/cpblocked.c
src/WtdLogRank.c
src/StCu2Bnds.c
src/mystack.c
src/AsyPwrGSD.c
src/drift.c
src/cmptdnsty.c
src/MySurvFit.c
src/SimPwrGSD.c
src/trand.c
src/driftfu.c
src/cmptpwrgsd.c
src/grpseqbnds.c
src/htilde.c
src/intsurvdiff.c
src/Finv.c
src/Dnsties.c
src/agghaz.c

Questions? Problems? Suggestions? or email at ian@mutexlabs.com.

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All documentation is copyright its authors; we didn't write any of that.