RepeatABEL-package: GWAS for repeated observations on related individuals

Description Details Author(s) References See Also

Description

The RepeatABEL package computes score statistic based p-values for a linear mixed model including random polygenic effects and a random effect for repeated measurements. A p-value is computed for each marker and the null hypothesis tested is that the additive marker effect is zero.

Details

Package: RepeatABEL
Type: Package
Version: 1.1
Date: 2016-08-19
License: GPL
Depends: hglm, GenABEL

The core function is rGLS that requires an GenABEL object as input and produces an GenABEL object.

Author(s)

Lars Ronnegard

Maintainer: Lars Ronnegard <lrn@du.se>

References

Ronnegard et al. (2016). Increasing the power of genome wide association studies in natural populations using repeated measures: evaluation and implementation.. Methods in Ecology and Evolution, 7, 792-799.

Husby et al. (2015) Genome-wide association mapping in a wild avian population identifies a link between genetic and phenotypic variation in a life history trait. Proceedings of the Royal Society B: Biological Sciences, 282(1806), 20150156.

Ronnegard, Shen & Alam (2010). hglm: A Package for Fitting Hierarchical Generalized Linear Models. The R Journal, 2(2), 20-28.

See Also

rGLS


RepeatABEL documentation built on May 2, 2019, 6:08 p.m.