This data frame gives the results of 10 separate case–control studies on the association of breast cancer and whether a woman had breast–fed children.
A data frame with 20 observations on the following 4 variables.
Factor indicating the study from which data was taken
Whether women had breast–fed children (lactated)
Number of women with breast cancer
Number of women without breast cancer
Meta–analysis refers to the analysis of analyses. When the main results of studies can be cast into 2x2 tables of counts, it is natural to combine individual odds ratios with a logistic regression model that includes a factor to account for different odds from the different studies. In addition, the odds ratio itself might differ slightly among studies because of different effects on different populations or different research techniques. One approach for dealing with this is to suppose an underlying common odds ratio and to model between–study variability as extra–binomial variation.
Ramsey, F.L. and Schafer, D.W. (2013). The Statistical Sleuth: A Course in Methods of Data Analysis (3rd ed), Cengage Learning.
Data gathered from various sources by Karolyn Kolassa as part of a Master's project, Oregon State University.