Description Usage Arguments Value Author(s) References
Find the false discovery rate for each gene in each cell-type.
1 | findSigGene(G, cc, y, rhat, csSAMData)
|
G |
Gene expression matrix of heterogenous tissue measurements |
cc |
Matrix of cell-frequency measures per person |
y |
Numeric group association of each sample. Either 1 or 2. |
rhat |
Matrix of cell-specific contrasts for each gene in each cell-type as computed for the original group classification. |
csSAMData |
List object returned from fdrCsSAM. |
A matrix size k by g where k is the number of cell-types and g is the number of genes. For each cell in the matirx, listed is the FDR of the gene for a difference in a given cell-type.
Shai Shen-Orr, Rob Tibshirani, Narasimhan Balasubramanian, David Wang
Shen-Orr SS, Tibshirani R, Khatri P, Bodian DL, Staedtler F, Perry NM, Hastie T, Sarwal MM, Davis MM and Butte AJ (2010). "Cell type-specific gene expression differences in complex tissues." _Nature methods_, *7*(4), pp. 287-9. ISSN 1548-7105, <URL: http://dx.doi.org/10.1038/nmeth.1439>, <URL: http://www.ncbi.nlm.nih.gov/pubmed/20208531>.
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