Golub (1999) Data...

Description

Golub (1999) Data Golub et al. (1999) data on gene expression profiles of 38 patients suffering from acute leukemia and a validation sample of 34 patients.

Details

The original data of Golub et al. (1999) were preprocessed as follows: genes that were called 'absent' in all samples were removed from the data sets, since these measurements are considered unreliable by the manufacturer of the technology. Negative measurements in the data were set to 1.

The resulting data frame contains 5327 genes of the 6817 originally reported by Golub et al. (1999).

Note

Luc Wouters et al. (2003), p. 1134 contains a typo concerning the sample sizes of AML- and ALL-type and erroneously reported

References

Luc Wouters et al. (2003). Graphical Exploration of Gene Expression Data: A Comparative Study of Three Multivariate Methods, Biometrics, 59, 1131-1139.