nebula-package: Negative Binomial Mixed Models Using Large-Sample...
In nebula: Negative Binomial Mixed Models Using Large-Sample Approximation for Differential Expression Analysis of ScRNA-Seq Data
Description
Details
Author(s)
References
Examples
Description
A fast negative binomial mixed model for conducting association analysis of multi-subject single-cell data. It can be used for identifying marker genes, differential expression and co-expression analyses. The model includes subject-level random effects to account for the hierarchical structure in multi-subject single-cell data.
Details
nebula is an R package for performing association analysis using a fast negative binomial mixed model for multi-subject single-cell data.
Author(s)
Liang He
Maintainer: Liang He <liang.he@duke.edu>
References
He. L, Kulminski, A.M., NEBULA: a fast negative binomial mixed model for differential expression and co-expression analysis of large-scale single-cell data. 2020
Examples
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library(nebula)
data(sample_data)
pred = model.matrix(~X1+X2+cc,data=sample_data$pred)
re = nebula(count=sample_data$count,id=sample_data$sid,pred=pred)
nebula documentation built on Sept. 24, 2021, 3 a.m.
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Description Details Author(s) References Examples
Description
A fast negative binomial mixed model for conducting association analysis of multi-subject single-cell data. It can be used for identifying marker genes, differential expression and co-expression analyses. The model includes subject-level random effects to account for the hierarchical structure in multi-subject single-cell data.
Details
nebula is an R package for performing association analysis using a fast negative binomial mixed model for multi-subject single-cell data.
Author(s)
Liang He
Maintainer: Liang He <liang.he@duke.edu>
References
He. L, Kulminski, A.M., NEBULA: a fast negative binomial mixed model for differential expression and co-expression analysis of large-scale single-cell data. 2020
Examples
1 2 3 4 | library(nebula)
data(sample_data)
pred = model.matrix(~X1+X2+cc,data=sample_data$pred)
re = nebula(count=sample_data$count,id=sample_data$sid,pred=pred)
|
R Package Documentation
Browse R Packages
We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
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