kd: Kidney disease data

In pa4bayesmeta: Prior Accuracy for Bayesian Meta-Analysis

Description

Meta-analysis data set including 2 controlled studies comparing Belatacept versus Ciclosporin A for prophylaxis of graft rejection in adults receiving a renal transplant. The effect estimates of interest are (log) hazard ratios.

Usage

data(kd)

Format

A data frame with 2 observations on the following 3 variables:

study

character string, label of the study

y

numeric, log hazard ratio estimate for the study

sigma

numeric, standard error of the log hazard ratio estimate for of the study

Details

This data set was originally analyzed by the Institute for Quality and Efficiency in Health Care (2015) and reanalyzed by Bender et al. (2018).

Both studies included in this data set provide evidence for a benefit of Belatacept compared to Ciclosporin A. In the original analysis, no pooling of the study results was done due to large heterogeneity.

Source

Bender, R., Friede, T., Koch, A., Kuss, O., Schlattmann, P., Schwarzer, G., Skipka, G. (2018). Methods for evidence synthesis in the case of very few studies. Research Synthesis Methods 9(3), 382–392. https://doi.org/10.1002/jrsm.1297

References

Institute for Quality and Efficiency in Health Care (2015). Belatacept – Nutzenbewertung gemaess Paragraph 35a SGB V, Auftrag A15-25, Version 1.0 vom 13.10.2015. https://www.iqwig.de/projekte/a15-25.html

Examples

data(kd)
str(kd)
# forest plot
forest(x = kd$y, sei = kd$sigma, xlab = "log hazard ratio")

pa4bayesmeta documentation built on Aug. 1, 2021, 3 p.m.