rieger: Radiation (UV and IR) response data of Reiger et al PNAS...
In rieger: Radiation data of Reiger et al (2004)

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Peripheral blood lymphocytes from a total of 57 patients were immortalized with Epstein-Barr virus. Fourteen radiation-therapy patients suffered unusual levels of radiation toxicity (RadS). Thirteen radiation-therapy patients with limited toxicity (RadC) were enrolled as controls. Fifteen patients diagnosed with skin cancer before age 40 (SkCa) were used as a second group of controls. Fifteen healthy subjects without any history of cancer (NoCa) were matched to the skin cancer patients and used as a third group of controls.

1	data(rieger)

The rownames of the phenodata and colnames of the expression matrix are the GEO sample names. There are 4 covariates:

state: hc="healthy control",skc="skin cancer control", notox="limited toxicity control",tox="toxicity".
UV: 0 or 10 J/m^2
IR: 0 or 5 Gy
individual: code for individual

Cells were exposed to mock treatment (Mock), ultra-violet radiation (UV), or ionizing radiation (IR). For UV radiation treatment, cells were exposed to 10 J/m^2 and harvested for RNA 24 hours later. For IR treatment, cells were exposed to 5 Gy of IR and harvested for RNA 4 hours later. U95av2 data analyzed with Affymetrix MAS version 4.0.

ExpressionSet obtained as rieger <- GDS2eSet(getGEO("GDS968")). Description and Details obtained verbatim from http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE1725.

Rieger KE, Hong WJ, Tusher VG, Tang J et al. Toxicity from radiation therapy associated with abnormal transcriptional responses to DNA damage. Proc Natl Acad Sci U S A 2004 Apr 27;101(17):6635-40. PMID: 15096622. The published manuscript can be found at http://www.pnas.org/cgi/doi/10.1073/pnas.0307761101.