surrosurv: Evaluation of Failure Time Surrogate Endpoints in Individual Patient Data Meta-Analyses

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Provides functions for the evaluation of surrogate endpoints when both the surrogate and the true endpoint are failure time variables. The approaches implemented are: (1) the two-step approach (Burzykowski et al, 2001) <DOI:10.1111/1467-9876.00244> with a copula model (Clayton, Plackett, Hougaard) at the first step and either a linear regression of log-hazard ratios at the second step (either adjusted or not for measurement error); (2) mixed proportional hazard models estimated via mixed Poisson GLM.

Author
Federico Rotolo [aut, cre], Xavier Paoletti [ctr], Marc Buyse [ctr], Tomasz Burzykowski [ctr], Stefan Michiels [ctr]
Date of publication
2016-12-09 15:31:06
Maintainer
Federico Rotolo <federico.rotolo@gustaveroussy.fr>
License
GPL-2
Version
1.1.6

View on R-Forge

Man pages

convergence
Assesses the convergence of fitted models for surrogacy...
gastadv
Individual data from the advanced GASTRIC meta-analysis
loocv
Leave-one-trial-out cross-validation for treatment effect...
poissonize
Tranform survival data for fitting a Poisson model
simData
Generate survival times for two endpoints in a meta-analysis...
ste
Surrogate threshold effect
surrosurv
Fit and print the models for evaluating the surrogacy...
surrosurv-package
\Sexpr[results=rd,stage=build]{tools:::Rd_package_title("surrosurv")}

Files in this package

surrosurv/DESCRIPTION
surrosurv/NAMESPACE
surrosurv/NEWS
surrosurv/R
surrosurv/R/convergence.R
surrosurv/R/copulas_functions.R
surrosurv/R/loocv.R
surrosurv/R/poisson_functions.R
surrosurv/R/poissonize.R
surrosurv/R/predict.R
surrosurv/R/simData.R
surrosurv/R/surrosurv.R
surrosurv/TODO
surrosurv/build
surrosurv/build/partial.rdb
surrosurv/build/vignette.rds
surrosurv/data
surrosurv/data/gastadv.RData
surrosurv/inst
surrosurv/inst/doc
surrosurv/inst/doc/copulas.Rnw
surrosurv/inst/doc/copulas.pdf
surrosurv/man
surrosurv/man/convergence.Rd
surrosurv/man/gastadv.Rd
surrosurv/man/loocv.Rd
surrosurv/man/poissonize.Rd
surrosurv/man/simData.Rd
surrosurv/man/ste.Rd
surrosurv/man/surrosurv-package.Rd
surrosurv/man/surrosurv.Rd
surrosurv/vignettes
surrosurv/vignettes/copulas.Rnw
surrosurv/vignettes/loocv-1.pdf
surrosurv/vignettes/poissonize-1.pdf
surrosurv/vignettes/predictions-1.pdf
surrosurv/vignettes/refs.bib
surrosurv/vignettes/surrosurv.pdf
surrosurv/vignettes/surrosurv.tex
surrosurv/vignettes/survCurves-1.pdf