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surrosurv: Evaluation of Failure Time Surrogate Endpoints in Individual Patient Data Meta-Analyses
Provides functions for the evaluation of surrogate endpoints when both the surrogate and the true endpoint are failure time variables. The approaches implemented are: (1) the two-step approach (Burzykowski et al, 2001) <DOI:10.1111/1467-9876.00244> with a copula model (Clayton, Plackett, Hougaard) at the first step and either a linear regression of log-hazard ratios at the second step (either adjusted or not for measurement error); (2) mixed proportional hazard models estimated via mixed Poisson GLM.
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Package details |
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| Author | Federico Rotolo [aut, cre], Xavier Paoletti [ctr], Marc Buyse [ctr], Tomasz Burzykowski [ctr], Stefan Michiels [ctr] |
| Maintainer | Federico Rotolo <federico.rotolo@gustaveroussy.fr> |
| License | GPL-2 |
| Version | 1.1.16 |
| Package repository | View on R-Forge |
| Installation |
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