survGenesInterim: Simulation of Survival Studies with Microarray Data

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The main part of this package is the simulation of a survival study based on simulated gene expression level data and simulated patient data. Functions to generate such gene expression level data and patient data are included as well. Resulting error rate (FDR) and power rate can be visualized. Thus, this package can be used for sample size or power estimations in the planning of a study.

Author
Andreas Leha, Klaus Jung, Tim Beissbarth
Date of publication
2012-03-06 21:00:29
Maintainer
Andreas Leha <andreas.leha@med.uni-goettingen.de>
License
GPL2
Version
1.0

View on R-Forge

Man pages

createMeanResultTable
Restructure the Simulation Output for Display
estimateAPR
Simple Estimation of the Average Power Rate
estimateFDR
Simple Estimation of the False Discovery Rate
generateExpressionData
Generate Gene Expression Data
generatePatientData
Generate Patient Data
interimTrial
'interimTrial' simulates one survival study with interim...
interimTrialSimulation
Simulation of Several Survival Studies With the Same...
plotgendat
This function visualizes the differential expression (fold...
plotinterimAPR
This function takes the result of either 'interimTrial' or...
plotinterimFDR
This function takes the result of either 'interimTrial' or...
plotinterimStops
This function creates a barplot showing at which interim...
plotpatdat
This function visualizes the patient data that is generated...
survGenesInterim-package
Simulation of Survival Studies with Microarray Data

Files in this package

survGenesInterim
survGenesInterim/R
survGenesInterim/R/interim_and_survival_package_functions.R
survGenesInterim/NAMESPACE
survGenesInterim/inst
survGenesInterim/inst/doc
survGenesInterim/inst/doc/survGenesInterim.pdf
survGenesInterim/inst/doc/survGenesInterim.Rnw
survGenesInterim/DESCRIPTION
survGenesInterim/man
survGenesInterim/man/plotinterimStops.Rd
survGenesInterim/man/generatePatientData.Rd
survGenesInterim/man/estimateAPR.Rd
survGenesInterim/man/interimTrialSimulation.Rd
survGenesInterim/man/plotpatdat.Rd
survGenesInterim/man/estimateFDR.Rd
survGenesInterim/man/createMeanResultTable.Rd
survGenesInterim/man/plotinterimAPR.Rd
survGenesInterim/man/survGenesInterim-package.Rd
survGenesInterim/man/plotinterimFDR.Rd
survGenesInterim/man/generateExpressionData.Rd
survGenesInterim/man/plotgendat.Rd
survGenesInterim/man/interimTrial.Rd