ASSIGN is a computational tool to evaluate the pathway deregulation/activation status in individual patient samples. ASSIGN employs a flexible Bayesian factor analysis approach that adapts predetermined pathway signatures derived either from knowledge-based literature or from perturbation experiments to the cell-/tissue-specific pathway signatures. The deregulation/activation level of each context-specific pathway is quantified to a score, which represents the extent to which a patient sample encompasses the pathway deregulation/activation signature.
|Ying Shen, Andrea H. Bild, W. Evan Johnson, and Mumtehena Rahman
|Bayesian GeneExpression Pathways Software
|Ying Shen <firstname.lastname@example.org>, W. Evan Johnson <email@example.com>, David Jenkins <firstname.lastname@example.org>, Mumtehena Rahman <email@example.com>
|MIT + file LICENSE
|View on Bioconductor
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