ASSIGN: Adaptive Signature Selection and InteGratioN (ASSIGN)
Version 1.12.0

ASSIGN is a computational tool to evaluate the pathway deregulation/activation status in individual patient samples. ASSIGN employs a flexible Bayesian factor analysis approach that adapts predetermined pathway signatures derived either from knowledge-based literatures or from perturbation experiments to the cell-/tissue-specific pathway signatures. The deregulation/activation level of each context-specific pathway is quantified to a score, which represents the extent to which a patient sample encompasses the pathway deregulation/activation signature.

Package details

AuthorYing Shen, Andrea H. Bild, W. Evan Johnson, and Mumtehena Rahman
Bioconductor views Bayesian GeneExpression Pathways Software
MaintainerYing Shen <>, W. Evan Johnson <>, David Jenkins <>, Mumtehena Rahman <>
LicenseMIT + file LICENSE
Package repositoryView on Bioconductor
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ASSIGN documentation built on May 31, 2017, 11:48 a.m.