combine-method: combine method

In DMCFB: Differentially Methylated Cytosines via a Bayesian Functional Approach

Description

combine two BSDMC-class or two BSDMC-class

Usage

combine(obj1, obj2)

## S4 method for signature 'BSDMC,BSDMC'
combine(obj1, obj2)

Arguments

obj1	A BSDMC-class
obj2	A BSDMC-class

Value

A BSDMC-class or BSDMC-class

Author(s)

Farhad Shokoohi <[e-mail]>

Examples

set.seed(1980)
nr <- 150
nc <- 8
metht <- matrix(as.integer(runif(nr * nc * 2, 0, nr)), nr)
methc <- matrix(
  rbinom(n = nr * nc, c(metht), prob = runif(nr * nc * 2)),
  nr, nc * 2
)
methl <- methc / metht
r1 <- GRanges(rep("chr1", nr), IRanges(1:nr, width = 1), strand = "*")
names(r1) <- 1:nr
cd1 <- DataFrame(Group = rep("G1", each = nc), row.names = LETTERS[1:nc])
OBJ1 <- cBSDMC(
  rowRanges = r1, methReads = methc[, 1:nc], totalReads = metht[, 1:nc],
  methLevels = methl[, 1:nc], colData = cd1
)
cd2 <- DataFrame(
  Group = rep("G2", each = nc),
  row.names = LETTERS[nc + 1:nc]
)
OBJ2 <- cBSDMC(
  rowRanges = r1, methReads = methc[, nc + 1:nc], totalReads =
    metht[, nc + 1:nc], methLevels = methl[, nc + 1:nc], colData = cd2
)
OBJ3 <- combine(OBJ1, OBJ2)
OBJ3

DMCFB documentation built on Nov. 8, 2020, 8:03 p.m.