EmpiricalBrownsMethod: Uses Brown's method to combine p-values from dependent tests

Combining P-values from multiple statistical tests is common in bioinformatics. However, this procedure is non-trivial for dependent P-values. This package implements an empirical adaptation of Brown’s Method (an extension of Fisher’s Method) for combining dependent P-values which is appropriate for highly correlated data sets found in high-throughput biological experiments.

Package details

AuthorWilliam Poole
Bioconductor views GeneExpression Pathways StatisticalMethod
MaintainerDavid Gibbs <dgibbs@systemsbiology.org>
LicenseMIT + file LICENSE
Version1.18.0
URL https://github.com/IlyaLab/CombiningDependentPvaluesUsingEBM.git
Package repositoryView on Bioconductor
Installation Install the latest version of this package by entering the following in R:
if (!requireNamespace("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("EmpiricalBrownsMethod")

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EmpiricalBrownsMethod documentation built on Nov. 8, 2020, 8:16 p.m.