EmpiricalBrownsMethod: Uses Brown's method to combine p-values from dependent tests

Combining P-values from multiple statistical tests is common in bioinformatics. However, this procedure is non-trivial for dependent P-values. This package implements an empirical adaptation of Brown’s Method (an extension of Fisher’s Method) for combining dependent P-values which is appropriate for highly correlated data sets found in high-throughput biological experiments.

Package details

AuthorWilliam Poole
Bioconductor views GeneExpression Pathways StatisticalMethod
MaintainerDavid Gibbs <dgibbs@systemsbiology.org>
LicenseMIT + file LICENSE
URL https://github.com/IlyaLab/CombiningDependentPvaluesUsingEBM.git
Package repositoryView on Bioconductor
Installation Install the latest version of this package by entering the following in R:

Try the EmpiricalBrownsMethod package in your browser

Any scripts or data that you put into this service are public.

EmpiricalBrownsMethod documentation built on April 29, 2020, 4:19 a.m.