EmpiricalBrownsMethod: Uses Brown's method to combine p-values from dependent tests

Combining P-values from multiple statistical tests is common in bioinformatics. However, this procedure is non-trivial for dependent P-values. This package implements an empirical adaptation of Brown’s Method (an extension of Fisher’s Method) for combining dependent P-values which is appropriate for highly correlated data sets found in high-throughput biological experiments.

Author
William Poole
Date of publication
None
Maintainer
David Gibbs <dgibbs@systemsbiology.org>
License
MIT + file LICENSE
Version
1.2.0
URLs

View on Bioconductor

Man pages

ebmTestData
Data used in tests and examples.
empiricalBrownsMethod
The Empirical Browns Method For Combining P-values
kostsMethod
The Kost Method For Combining P-values

Files in this package

EmpiricalBrownsMethod/DESCRIPTION
EmpiricalBrownsMethod/LICENSE
EmpiricalBrownsMethod/NAMESPACE
EmpiricalBrownsMethod/R
EmpiricalBrownsMethod/R/ebm.R
EmpiricalBrownsMethod/build
EmpiricalBrownsMethod/build/vignette.rds
EmpiricalBrownsMethod/data
EmpiricalBrownsMethod/data/ebmTestData.RData
EmpiricalBrownsMethod/inst
EmpiricalBrownsMethod/inst/NEWS
EmpiricalBrownsMethod/inst/doc
EmpiricalBrownsMethod/inst/doc/ebmVignette.R
EmpiricalBrownsMethod/inst/doc/ebmVignette.Rmd
EmpiricalBrownsMethod/inst/doc/ebmVignette.html
EmpiricalBrownsMethod/man
EmpiricalBrownsMethod/man/ebmTestData.Rd
EmpiricalBrownsMethod/man/empiricalBrownsMethod.Rd
EmpiricalBrownsMethod/man/kostsMethod.Rd
EmpiricalBrownsMethod/tests
EmpiricalBrownsMethod/tests/test-all.R
EmpiricalBrownsMethod/tests/testthat
EmpiricalBrownsMethod/tests/testthat/test_ebm_main.R
EmpiricalBrownsMethod/vignettes
EmpiricalBrownsMethod/vignettes/ebmVignette.Rmd
EmpiricalBrownsMethod/vignettes/ebmVignette.md