The FEM package performs a systems-level integrative analysis of DNA methylation and gene expression data. It seeks modules of functionally related genes which exhibit differential promoter DNA methylation and differential expression, where an inverse association between promoter DNA methylation and gene expression is assumed. For full details, see Jiao et al Bioinformatics 2014.
|Author||Andrew E. Teschendorff and Zhen Yang|
|Bioconductor views||DifferentialExpression DifferentialMethylation NetworkEnrichment SystemsBiology|
|Maintainer||Zhen Yang <[email protected]>|
|Package repository||View on Bioconductor|
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