The FEM package performs a systems-level integrative analysis of DNA methylation and gene expression data. It seeks modules of functionally related genes which exhibit differential promoter DNA methylation and differential expression, where an inverse association between promoter DNA methylation and gene expression is assumed. For full details, see Jiao et al Bioinformatics 2014.
|Author||Andrew E. Teschendorff and Zhen Yang|
|Bioconductor views||DifferentialExpression DifferentialMethylation NetworkEnrichment SystemsBiology|
|Date of publication||None|
|Maintainer||Zhen Yang <email@example.com>|
DoEpiMod: Identifies differential DNA methylation network hotspots.
DoExpMod: Identifies differential mRNA expression network hotspots.
DoFEMbi: Identifies interactome hotspots of differential promoter DNAm...
DoIntEpi450k: Integrates statistics of differential DNA methylation for a...
DoIntExp: Integrates statistics of differential expression for a...
DoIntFEM450k: Integrates statistics of differential DNA methylation and...
FemModShow: Generates a figure showing the inferred FEM module(s)
FEM-package: Identification of interactome hotspots of differential...
GenStatM: Generation of differential DNA methylation statistics
GenStatMsp: Generation of differential DNA methylation statistics for...
GenStatR: Generation of differential expression statistics
probe450kfemanno: Processed annotation of Illumina 450k probes for use in the...
probeEPICfemanno: Processed annotation of Illumina EPIC probes for use in the...
Realdata: A dataset object derived from real DNA methylation and gene...
Toydata: Artificial data set.
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