FEM: Identification of Functional Epigenetic Modules

The FEM package performs a systems-level integrative analysis of DNA methylation and gene expression data. It seeks modules of functionally related genes which exhibit differential promoter DNA methylation and differential expression, where an inverse association between promoter DNA methylation and gene expression is assumed. For full details, see Jiao et al Bioinformatics 2014.

Package details

AuthorAndrew E. Teschendorff and Zhen Yang
Bioconductor views DifferentialExpression DifferentialMethylation NetworkEnrichment SystemsBiology
MaintainerZhen Yang <yangzhen@picb.ac.cn>
LicenseGPL (>=2)
Version3.15.0
Package repositoryView on Bioconductor
Installation Install the latest version of this package by entering the following in R:
if (!requireNamespace("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("FEM")

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FEM documentation built on April 28, 2020, 8:56 p.m.