LPSData: LPSData

In GateFinder: Projection-based Gating Strategy Optimization for Flow and Mass Cytometry

Description

A dataset of two sets of scores (particularly, correlation with protection against HIV and overlap with the Naive T-cell population) assigned to immunophenotypes measured by flow cytometry. 10 markers were measured: KI-67, CD28, CD45RO, CD8, CD4, CD57, CCR5, CD27, CCR7, and CD127.

Usage

data(LPSData)

Details

This dataset consists of a matrix and two vectors:

rawdata The transformed expression values extracted from the original FCS file.

prop.markers the indexes of markers that should be considered for the gating strategy.

marker.names name of all markers (columns of matrix rawdata).

Author(s)

Nima Aghaeepour <[e-mail]> and Erin F. Simonds <[e-mail]>.

References

Bendall, Sean C., et al. "Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum." Science 332.6030 (2011): 687-696.

Examples

library(flowCore)

data(LPSData)

plot(exprs(rawdata)[,15:16],xlab=marker.names[15],ylab=marker.names[16])

GateFinder documentation built on Nov. 8, 2020, 7:53 p.m.