testMEDMEset: Dataset of class MEDMEset for testing MEDME

Description Usage Format References

Description

This dataset contains a subset of the data reported in references. It contains normalized un-smoothed probe-level MeDIP enrichment for almost 50000 probes. This is a random subset of a custom Nimblegen chromosome X tiling array. It is a two channels array with an resolution of 100bp and oligos of 60nt. The M value is reported only. The fullyMet column of the logR slot contains data from a calibration experiments where MeDIP has been applied to a fully methylated sample. The last two columns NBMEL and YUSAC2 contain DNA-methylation experimental data for two cell strains: NBMEL are newborn normal melanocytes cells and YUSAC2 a melanoma strain. Data was processed with within and between array normalization. The full dataset contains almost 380K probes. See references for details. Chromosome, genomic position and logR of probes can be accessed with the methods chr, pos and logR respectively.

Please note that the original genomic coordinates were mapped to the hg17 human genome. These have been converted to hg18 using the LiftOver USCS tool available online for batch conversion.

Usage

1

Format

MEDMEset

References

http://genome.cshlp.org/cgi/content/abstract/gr.080721.108v1


MEDME documentation built on Nov. 8, 2020, 5:31 p.m.

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