PAA: PAA (Protein Array Analyzer)

PAA imports single color (protein) microarray data that has been saved in gpr file format - esp. ProtoArray data. After preprocessing (background correction, batch filtering, normalization) univariate feature preselection is performed (e.g., using the "minimum M statistic" approach - hereinafter referred to as "mMs"). Subsequently, a multivariate feature selection is conducted to discover biomarker candidates. Therefore, either a frequency-based backwards elimination aproach or ensemble feature selection can be used. PAA provides a complete toolbox of analysis tools including several different plots for results examination and evaluation.

Getting started

Package details

AuthorMichael Turewicz [aut, cre], Martin Eisenacher [ctb, cre]
Bioconductor views Classification Microarray OneChannel Proteomics
MaintainerMichael Turewicz <>, Martin Eisenacher <>
LicenseBSD_3_clause + file LICENSE
Package repositoryView on Bioconductor
Installation Install the latest version of this package by entering the following in R:
if (!requireNamespace("BiocManager", quietly = TRUE))


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PAA documentation built on Nov. 8, 2020, 8:30 p.m.