st000336: Targeted LC/MS of urine from boys with DMD and controls

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Duchenne Muscular Dystrophy (DMD) is an X-linked recessive form of muscular dystrophy that affects males via a mutation in the gene for the muscle protein, dystrophin. Progression of the disease results in severe muscle loss, ultimately leading to paralysis and death. Steroid therapy has been a commonly employed method for reducing the severity of symptoms. This study aims to quantify the urine levels of amino acids and organic acids in patients with DMD both with and without steroid treatment. Track the progression of DMD in patients who have provided multiple urine samples.




A MSnSet object: 57 samples, 31 metabolites, 1 covariable and 2 groups (Controls and DMD).


31 urine metabolites.


Steroid status.


POMA documentation built on Nov. 8, 2020, 6:26 p.m.