Hart: Hart
In SMAD: Statistical Modelling of AP-MS Data (SMAD)
Description
Usage
Arguments
Value
Author(s)
References
Examples
Description
Hart
Scoring algorithm based on a hypergeometric distribution error model (Hart et al.,2007).
Usage
1
Hart(datInput)
Arguments
datInput
A dataframe with column names: idRun, idPrey.
Each row represent one unique protein captured in one pull-down experiment.
Value
A dataframe consists of pairwise combindation of preys identified in
the input with Hart scores indicating interacting probabilities computed from
negative log transformed Hypergeometric test P-values.
Author(s)
Qingzhou Zhang, zqzneptune@hotmail.com
References
Hart, G. Traver, Insuk Lee, and Edward M. Marcotte.
'A high-accuracy consensus map of yeast protein complexes reveals modular
nature of gene essentiality.' BMC bioinformatics 8.1 (2007): 236.
https://doi.org/10.1186/1471-2105-8-236
Examples
1
2
3
data(TestDatInput)
datScore <- Hart(TestDatInput)
head(datScore)
SMAD documentation built on Nov. 8, 2020, 8:24 p.m.
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Description Usage Arguments Value Author(s) References Examples
Description
Hart Scoring algorithm based on a hypergeometric distribution error model (Hart et al.,2007).
Usage
1 | Hart(datInput)
|
Arguments
datInput |
A dataframe with column names: idRun, idPrey. Each row represent one unique protein captured in one pull-down experiment. |
Value
A dataframe consists of pairwise combindation of preys identified in the input with Hart scores indicating interacting probabilities computed from negative log transformed Hypergeometric test P-values.
Author(s)
Qingzhou Zhang, zqzneptune@hotmail.com
References
Hart, G. Traver, Insuk Lee, and Edward M. Marcotte. 'A high-accuracy consensus map of yeast protein complexes reveals modular nature of gene essentiality.' BMC bioinformatics 8.1 (2007): 236. https://doi.org/10.1186/1471-2105-8-236
Examples
1 2 3 | data(TestDatInput)
datScore <- Hart(TestDatInput)
head(datScore)
|
R Package Documentation
Browse R Packages
We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
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