STATegRa_data: STATegRa data

In STATegRa: Classes and methods for multi-omics data integration

Description

mRNA data (Block1), miRNA data (Block2) and the design matrix (ed), from STATegRa_S1, provides selected data downloaded from https://tcga-data.nci.nih.gov/docs/publications/gbm_exp/. The mapping between miRNA and mRNA (mapdata, available in STATegRa_S2) contains, as a processed matrix, selected information available from TargetScan; we selected the set of miRNA target predictions for humans for those miRNA-mRNA pairs where both miRNA and mRNA were in Block1 and Block2 respectively.

The PCA version of the data (Block1.PCA, Block2.PCA, ed.PCA; available in STATegRa_S3), provides a similar data-set to Block1, Block2 and ed data; however in this case the data has been processed in order to provide a pedagogic example of OmicsPCA. Results obtained from OmicsPCA (omicsCompAnalysis) with the existing data should not be taken as clinically valid.

Format

Two matrices with mRNA and miRNA expression data, a design matrix that describes both and a mapping between miRNA and genes.

Author(s)

David Gomez-Cabrero, Patricia Sebastian-Leon, Gordon Ball

Source

(a) See https://tcga-data.nci.nih.gov/docs/publications/gbm_exp/. (b) Gabor Csardi, targetscan.Hs.eg.db: TargetScan miRNA target predictions for human. R package version 0.6.1

Examples

data(STATegRa_S1)
data(STATegRa_S2)
data(STATegRa_S3)

STATegRa documentation built on Nov. 8, 2020, 5:26 p.m.