mRNA data (
Block1), miRNA data (
Block2) and the design matrix (
STATegRa_S1, provides selected data downloaded from https://tcga-data.nci.nih.gov/docs/publications/gbm_exp/. The mapping between miRNA and mRNA (
mapdata, available in
STATegRa_S2) contains, as a processed matrix, selected information available from TargetScan; we selected the set of miRNA target predictions for humans for those miRNA-mRNA pairs where both miRNA and mRNA were in
The PCA version of the data (
ed.PCA; available in
STATegRa_S3), provides a similar data-set to
ed data; however in this case the data has been processed in order to provide a pedagogic example of OmicsPCA. Results obtained from OmicsPCA (
omicsCompAnalysis) with the existing data should not be taken as clinically valid.
Two matrices with mRNA and miRNA expression data, a design matrix that describes both and a mapping between miRNA and genes.
David Gomez-Cabrero, Patricia Sebastian-Leon, Gordon Ball
(a) See https://tcga-data.nci.nih.gov/docs/publications/gbm_exp/.
(b) Gabor Csardi,
targetscan.Hs.eg.db: TargetScan miRNA target predictions for human. R package version 0.6.1
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