Description Usage Arguments Details Value References Examples
Computes drug signature scores. Also draws heatmap representing the average signature scores for each subtype.
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expr |
A |
pred |
A vector of predicted consensus molecular subtypes. |
gene.set |
A user-provided list of gene sets associated with drug response. Names of gene sets must follow the format of [DRUG NAME]_[RESISTANCE/RESPONSE]_[UP/DN] (e.g. CISPLATIN_RESISTANCE_DN). |
Drug signature scores are the average of expression values of genes included in gene sets from MSigDB.
A matrix of drug signature scores.
Liberzon, A. et al. (2011). Molecular signatures database (MSigDB) 3.0. Bioinformatics, 27, 1739-40.
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