Description Usage Arguments Value Author(s) References Examples
Find index for marker genes with largest coefficient of variation based on raw data.
1 | findRefinx(rawdata, nmarker=1000, sortBy = "var")
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rawdata |
A data matrix with rows representing features and columns represeting samples; or a SummarizedExperiment object. |
nmarker |
Desired number of markers after selection. Default is 1000. |
sortBy |
Desired method to select features. "var" represents selecting by largest variance. "cv" represents selecting by largest coefficients of variation. Default is "var". |
A vector of index for the selected markers.
Ziyi Li <ziyi.li@emory.edu>
Ziyi Li, Zhijin Wu, Peng Jin, Hao Wu. "Dissecting differential signals in high-throughput data from complex tissues."
1 2 3 | Y_raw <- matrix(runif(5000*20, 0, 1), 5000, 20)
idx <- findRefinx(Y_raw, nmarker=500)
idx2 <- findRefinx(Y_raw, nmarker=500, sortBy = "cv")
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