countGenos-methods: Count occurences of genotypes

Description Usage Arguments Value Author(s) See Also Examples

Description

Counts the total occurences of a set of genotypes by row in a matrix of genotype. All given genotypes are counted toward a single total (e.g. grand total of c("0/0", "0|0")), while other genotypes are silently ignored.

Usage

1
2
3
## S4 method for signature 'ExpandedVCF'
countGenos(
    x, genos, pheno = NULL, level = NULL)

Arguments

x

ExpandedVCF object.

genos

character vector of genotypes to count (toward a common unique total).

pheno

If x is an ExpandedVCF object, phenotype in colnames(colData(x)).

level

If x is an ExpandedVCF object, phenotype level in colData(x)[,pheno].

Value

An integer vector representing the aggregated count of the given genotypes in each row.

Author(s)

Kevin Rue-Albrecht

See Also

VCF

Examples

 1
 2
 3
 4
 5
 6
 7
 8
 9
10
11
12
13
14
15
16
17
18
19
20
21
# Example data ----

# VCF file
vcfFile <- system.file("extdata", "moderate.vcf", package = "TVTB")

# Phenotype file
phenoFile <- system.file("extdata", "moderate_pheno.txt", package = "TVTB")
phenotypes <- S4Vectors::DataFrame(read.table(phenoFile, TRUE, row.names = 1))

# TVTB parameters
tparam <- TVTBparam(Genotypes("0|0", c("0|1", "1|0"), "1|1"))

# Pre-process variants
vcf <- VariantAnnotation::readVcf(
    vcfFile, param = tparam, colData = phenotypes)
vcf <- VariantAnnotation::expand(vcf, row.names = TRUE)


# Example usage ----

vcf <- countGenos(vcf, het(tparam), "super_pop", "AFR")

TVTB documentation built on Nov. 1, 2018, 2:24 a.m.