methylation: CpG island DNA methylation array data

In TurboNorm: A fast scatterplot smoother suitable for microarray normalization

Description

CpG island DNA methylation array data of a neuro-ectodermal cell line that was treated with a demethylating agent

Usage

	data(methylation)

Format

"RGList" as defined in the package limma containing data from CpG island DNA methylation array data of a neuro-ectodermal cell line that was treated with a demethylating agent. The element "weights" of the "RGList" contains the subset of invariant fragments, those without methylation-sensitive restriction sites, as a logical vector.

Details

The data is extracted from a larger experiment described in van Iterson et al. Because the data is from a high-dense tiling array a random subset of the data was chosen for convenience in making the vignette.

References

van Iterson M, Duijkers FA, Meijerink JP, Admiraal P, van Ommen GJ, Boer JM, van Noesel MM, Menezes RX (2012). A novel and fast normalization method for high-density arrays. SAGMB, 11(4).

Examples

	data(methylation)

TurboNorm documentation built on Nov. 8, 2020, 6:46 p.m.