unrelatedIndividuals: Analysis designed to be applied over a group of unrelated...
In VariantFiltering: Filtering of coding and non-coding genetic variants

Description Usage Arguments Details Value Author(s) References See Also Examples

This function is designed to create an object to deepen into the variants presented by a group of unrelated individuals

## S4 method for signature 'VariantFilteringParam'
unrelatedIndividuals(param,
                                                       svparam=ScanVcfParam(),
                                                       BPPARAM=bpparam("SerialParam"))

`param`	A `VariantFilteringParam` object built from a multisample VCF file.
`svparam`	An instance of a `ScanVcfParam` object to enable analyzing a subset of variants and samples. This object is passed internally to a call to the `readVcf()` function in the `VariantAnnotation` package, see its help page for a complete description of this functionality.
`BPPARAM`	An object of class `BiocParallelParam` specifiying parameters related to the parallel execution of some of the tasks and calculations within this function. See function `bpparam()` from the `BiocParallel` package.

This function requires as an input a VariantFilteringParam class object built from an input multisample VCF file.

An object of class VariantFilteringResults including functional annotations on all variants.

Dei M. Elurbe and R. Castelo

Elurbe D.M., Mila, M., Castelo, R. The VariantFiltering package, in preparation.

autosomalRecessiveHomozygous autosomalRecessiveHeterozygous autosomalDominant deNovo xLinked VariantFilteringResults

## Not run: 

CEUvcf <- file.path(system.file("extdata", package="VariantFiltering"), "CEUtrio.vcf.bgz")
param <- VariantFilteringParam(vcfFilename=CEUvcf)
uInd <- unrelatedIndividuals(param)
uInd

## End(Not run)