ccmap: Combination Connectivity Mapping

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Finds drugs and drug combinations that are predicted to reverse or mimic gene expression signatures. These drugs might reverse diseases or mimic healthy lifestyles.

Author
Alex Pickering
Date of publication
None
Maintainer
Alex Pickering <alexvpickering@gmail.com>
License
MIT + file LICENSE
Version
1.0.0

View on Bioconductor

Man pages

get_dprimes
Extract unbiased effect sizes from meta-analysis by...
query_combos
Get overlap between query and predicted drug combination...
query_drugs
Get overlap between query and drug signatures.
sum_rowcolCumsum
Sum of cumulative sum computed over rows then columns of...

Files in this package

ccmap/DESCRIPTION
ccmap/LICENSE
ccmap/NAMESPACE
ccmap/R
ccmap/R/predict_combos.R
ccmap/R/query_combos.R
ccmap/R/query_drugs.R
ccmap/R/query_utils.R
ccmap/README.md
ccmap/build
ccmap/build/vignette.rds
ccmap/inst
ccmap/inst/doc
ccmap/inst/doc/ccmap-vignette.R
ccmap/inst/doc/ccmap-vignette.Rmd
ccmap/inst/doc/ccmap-vignette.html
ccmap/man
ccmap/man/get_dprimes.Rd
ccmap/man/query_combos.Rd
ccmap/man/query_drugs.Rd
ccmap/man/sum_rowcolCumsum.Rd
ccmap/tests
ccmap/tests/testthat
ccmap/tests/testthat.R
ccmap/tests/testthat/test-all.R
ccmap/vignettes
ccmap/vignettes/accuracy.png
ccmap/vignettes/ccmap-vignette.Rmd
ccmap/vignettes/meta-vs-cons.png