read.eisen: Read expression data from a file formatted for Eisen...

Description Usage Arguments Details Value Author(s) References

View source: R/read.eisen.R

Description

The input for Eisen-clustering is a slight variation of a tab delimited file. This method reads the expression data from such files as a matrix and provides optional additional information on the experiments as attributes.

Usage

1
    read.eisen(file,sep="\t",dec=".", format.check = TRUE)

Arguments

file

The relative or absolute path to the file to be read, as internally forwarded to the read.table function.

sep

Separator of fields, passed on to read.table.

dec

Passed on to read.table. This is particulary helpful for the interpretation of data from localised spreadsheet programs.

format.check

TRUE or FLASE: to disable file format check.

Details

The software of Michael Eisen and its plain tab separated format for the presentation of gene expression data prior to their clustering is supported by many hard- and software providers, both as an input for their tools and as resulting from the analysis and normalisation of the chip images. To be able to read and write this format, the Bioconductor suite is enabled to easily reanalyse or extend older experiments that might have been analysed with the Eisen tools before.

Value

A numerical matrix is returned. It is a complete analogue of the Eisen-format, except the descriptions, weights and other information being passed to attributes. The first row will be the column names, the first column will be the respective row name. A second row that has a first empty field is referred to via the attribute "second.row". A column NAME is stored in the attribute "NAME".

Author(s)

Steffen Moeller

References

Michael Eisen Lab http://rana.lbl.gov/

Michael Hoon's Cluster 3.0 http://bonsai.ims.u-tokyo.ac.jp/~mdehoon/software/cluster/

Eisen M.B., P.T. Spellman, P.O. Brown, and D. Botstein. 1998. Cluster analysis and display of genome-wide expression patterns. /Proc. Natl. Acad. Sci. USA /, 95:14863-14868.

De Hoon M.J.L., S. Imoto, J. Nolan, and S. Miyano. Open source clustering software. Bioinformatics *20* (9): 1453–1454 (2004).

Antoine Lucas and Sylvain Jasson, Using amap and ctc Packages for Huge Clustering, R News, 2006, vol 6, issue 5 pages 58-60.


ctc documentation built on Nov. 8, 2020, 5:11 p.m.