FR test for a single cell population pair comparison

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Description

Compute FR statistic for any two cell populations in flow cytometry data. Runtime of the FR test is quadratic in the number of events (nodes) totaling a single population pair comprison.

Usage

1
getFR(xx1, xx2)

Arguments

xx1

events of a single cell population, organized in a matrix or a data.frame of events (rows) by features (columns).

xx2

events of a single cell population, organized in a matrix or a data.frame of events (rows) by features (columns).

Value

ww FR statistic.

runs number of within-group subtrees (large number of runs indicate high degree of dissimilarity between the two cell populations being compared.

mu expected number of runs (when the two cell populations are similarly distributed).

sigma2 variance of runs.

pNorm p-values of the FR statitic assuming large sample asymptotic normal assumption.

Author(s)

Chiaowen Joyce Hsiao joyce.hsiao1@gmail.com

Examples

1
## see vignettes