bg.parameters.ns: Estimation of non-specific Binding Background Parameters

In gcrma: Background Adjustment Using Sequence Information

Description

An internal function to be used by gcrma

Usage

bg.parameters.ns(x,affinities,affinities2=NULL,affinities3=NULL,span=.2)

Arguments

x	PM or MM intensities after optical background correction, before non-specific-binding correction.
affinities	Probe affinities for probes with known sequences.Used to estimate the function between non-specific binding and affinities.
affinities2	Probe affinities for the probes whoes expected non-specific binding intensity is to be predicted.
affinities3	Probe affinities for another extra group of probes whoes expected non-specific binding intensity is to be predicted.
span	The span parameter passed to loess function

Value

a vector of same length as x.

Author(s)

Rafeal Irizarry, Zhijin (Jean) Wu

See Also

gcrma

gcrma documentation built on Nov. 8, 2020, 5:12 p.m.