golub: Gene expression dataset from Golub et al. (1999)

In hopach: Hierarchical Ordered Partitioning and Collapsing Hybrid (HOPACH)

Description

Gene expression data (3051 genes and 38 tumor mRNA samples) from the leukemia microarray study of Golub et al. (1999). Pre-processing was done as described in Dudoit et al. (2002). The R code for pre-processing is available in the file golub.R in the docs directory.

Usage

data(golub)

Value

golub	matrix of gene expression levels for the 38 tumor mRNA samples, rows correspond to genes (3051 genes) and columns to mRNA samples.
golub.cl	numeric vector indicating the tumor class, 27 acute lymphoblastic leukemia (ALL) cases (code 0) and 11 acute myeloid leukemia (AML) cases (code 1).
golub.gnames	a matrix containing the names of the 3051 genes for the expression matrix golub. The three columns correspond to the gene index, ID, and Name, respectively.

Source

Golub et al. (1999). Molecular classification of cancer: class discovery and class prediction by gene expression monitoring, Science, Vol. 286:531-537.
http://www-genome.wi.mit.edu/MPR/ .

References

S. Dudoit, J. Fridlyand, and T. P. Speed (2002). Comparison of discrimination methods for the classification of tumors using gene expression data. Journal of the American Statistical Association, Vol. 97, No. 457, p. 77–87.

hopach documentation built on Nov. 8, 2020, 4:54 p.m.