KRAS.Mutations: KRAS.Mutations

In iPAC: Identification of Protein Amino acid Clustering

Description

A matrix of the verified somatic mutations for KRAS from the COSMIC database.

Usage

data(KRAS.Mutations)

Format

There are 149 rows, each representing a different sample and 188 colums – one for each amino acid in the protein.

Source

Version 58 of the cosmic database was used.

References

S A Forbes, G Bhamra, S Bamford, E Dawson, C Kok, J Clements, A Menzies, J W Teague, P A Futreal, and M R Stratton. The catalogue of somatic mutations in cancer (COSMIC). Current Protocols in Human Genetics / Editorial Board, Jonathan L. Haines ... [et Al.], Chapter 10:Unit 10.11, April 2008. ISSN 1934-8258. doi: 10.1002/0471142905.hg1011s57.

URL http://www.ncbi.nlm.nih.gov/pubmed/18428421. PMID: 18428421.

Examples

data(KRAS.Mutations)

#Show the first 10 samples
KRAS.Mutations[1:10,]

#Show which samples had position 12 mutated
KRAS.Mutations[,12]

iPAC documentation built on Nov. 8, 2020, 7:48 p.m.