Description Usage Arguments Details Value Author(s) Examples
This function performs normalization and/or log2 transformation on gene expression data.
1 | preprocess(exprsObj,log2=TRUE, norm="ALL", destname=NULL)
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exprsObj |
An eSet object where its assay data will be normalized |
log2 |
Performs logarithmic transformation of base 2 prior to any normalzation. The default value is TRUE |
norm |
The user may define a specific normalization method rather than "ALL" which is the default case. The available abbreviations are described in the details section |
destname |
Here we define the destination path and the name of the jpeg file with the density plots. The default path is the working directory |
The available normalization methods are:
Mean-centering normalization "mc"
z-score normalization "z"
Quantile normalization "q"
Cyclic loess normalization "cl"
Mean-centering normalization and log2 transformation "mcL2"
z-score normalization and log2 transformation "zL2"
Quantile normalization and log2 transformation "qL2"
Cyclic loess normalization and log2 transformation "clL2"
rawdata |
The initial gene expression values |
mc.normdata |
The values after 'mean-centering' normalization |
z.normdata |
The values after 'z-score' normalization |
q.normdata |
The values after 'quantile' normalization |
cl.normdata |
The values after 'cyclic loess' normalization |
mcL2.normdata |
The values after 'mean-centering' normalization and log2 |
zL2.normdata |
The values after 'z-score' normalization and log2 |
qL2.normdata |
The values after 'quantile' normalization and log2 |
clL2.normdata |
The values after 'cyclic loess' normalization and log2 |
Argiris Sakellariou
1 2 3 4 5 | library(mAPKLData)
data(mAPKLData)
varLabels(mAPKLData)
breast <- sampling(Data=mAPKLData, valPercent=40, classLabels="type", seed=135)
normTrainData <- preprocess(exprsObj=breast$trainData)
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