This function downsamples the library sizes of a read counts table to the lowest library size, according to the methdology used in (Soneson and Delorenzi, BMC Bioinformatics, 2013).
the read counts table which is subjected to downsampling.
random seed for reproducible downsampling.
The downsampled counts matrix.
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## Dowload locally the file "bottomly_count_table.txt" from ## the ReCount database #download.file(paste("http://bowtie-bio.sourceforge.net/", # "recount/countTables/bottomly_count_table.txt",sep=""), # destfile="~/bottomly_count_table.txt") #M <- as.matrix(read.delim("~/bottomly_count_table.txt",row.names=1)) #D <- downsample.counts(M)
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