pxd010943: SWATH-MS Analysis of Gfi1-mutant bone marrow neutrophils

In msImpute: Imputation of label-free mass spectrometry peptides

Description

Contains Peak Area for peptides in PXD010943. This study investigates the proteomic alterations in bone marrow neutrophils isolated from 5-8 week old Gfi1+/-, Gfi1K403R/-, Gfi1R412X/-, and Gfi1R412X/R412X mice using the SWATH-MS technique. This dataset consists of 13 SWATH-DIA runs on a TripleTOF 5600 plus (SCIEX). Rows are peptides. Charge state variations are treated as distinct peptide species. Peptides with more than 4 observed intensity values are retained. The peptide.txt and experimentalDesignTemplate files can be downloaded as RDS object from https://github.com/soroorh/proteomicscasestudies. Code for data processing is provided in package vignette.

Usage

pxd010943

Format

A matrix

Source

http://proteomecentral.proteomexchange.org/cgi/GetDataset?ID=PXD010943

References

Muench DE, Olsson A, Ferchen K, Pham G, Serafin RA, Chutipongtanate S, Dwivedi P, Song B, Hay S, Chetal K, Trump-Durbin LR, Mookerjee-Basu J, Zhang K, Yu JC, Lutzko C, Myers KC, Nazor KL, Greis KD, Kappes DJ, Way SS, Salomonis N, Grimes HL, Mouse models of neutropenia reveal progenitor-stage-specific defects. Nature, 582(7810):109-114(2020)

msImpute documentation built on Nov. 8, 2020, 5:26 p.m.