nethet: A bioconductor package for high-dimensional exploration of biological network heterogeneity

Package nethet is an implementation of statistical solid methodology enabling the analysis of network heterogeneity from high-dimensional data. It combines several implementations of recent statistical innovations useful for estimation and comparison of networks in a heterogeneous, high-dimensional setting. In particular, we provide code for formal two-sample testing in Gaussian graphical models (differential network and GGM-GSA; Stadler and Mukherjee, 2013, 2014) and make a novel network-based clustering algorithm available (mixed graphical lasso, Stadler and Mukherjee, 2013).

Package details

AuthorNicolas Staedler, Frank Dondelinger
Bioconductor views Clustering GraphAndNetwork
MaintainerNicolas Staedler <>, Frank Dondelinger <>
Package repositoryView on Bioconductor
Installation Install the latest version of this package by entering the following in R:
if (!requireNamespace("BiocManager", quietly = TRUE))


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nethet documentation built on Nov. 8, 2020, 6:54 p.m.