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This package helps identify mRNAs that are overexpressed in subsets of tumors relative to normal tissue. Ideal inputs would be paired tumor-normal data from the same tissue from many patients (>15 pairs). This unsupervised approach relies on the observation that oncogenes are characteristically overexpressed in only a subset of tumors in the population, and may help identify oncogene candidates purely based on differences in mRNA expression between previously unknown subtypes.
Package details |
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Author | Daniel Pique, John Greally, Jessica Mar |
Bioconductor views | GeneExpression Sequencing |
Maintainer | Daniel Pique <daniel.pique@med.einstein.yu.edu> |
License | GPL-3 |
Version | 1.12.0 |
Package repository | View on Bioconductor |
Installation |
Install the latest version of this package by entering the following in R:
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